Day 2 :
- Others
Session Introduction
Isham Alzoub
Tehran University School of Surveying Geospatial Engineering
Title: Smart Spatial Analyses in Land Levelling
Biography:
Isham Alzoub has completed his PhD at the age of 27 years from Tehran University and studies from Doctor of Philosophy degree in agricultural Mechanization Engineering and he has completed his postdoctoral studies at the age of 40 years from School of Surveying Geospatial Engineering Department of Surveying and Geomatics Engineering, University of Tehran – Iran. Currently working as a General comission for scientific A gricultural Researh – Damascus – Syria. He has published more than 16 papers in reputed journals and has been serving as an editorial board member of repute.
Abstract:
Encyclopedia of Bioanalytical Methods for Bioavailability and Bioequivalence Studies of Pharmaceuticals (E-BABE): It is a unique encyclopedia involving bioanalytical methods for bioavailability and bioequivalence (BA/BE) studies of pharmaceuticals for suitable method selection with thousands of combinations and searches against these methods. Most scrutinized literature was collected from different sources including PubMed. This database has been curetted using published methods for all most all pharmaceuticals. Required information for regular method development/validation such as IUPAC name, structure, solubility, chromatographic conditions, instrumentation information like HPLC, LCMS detection parameters, sample preparations, recovery details, limit of detection and limit of quantification, Tmax, Cmax etc., for routine application in BA/BE studies of pharmaceuticals was incorporated including official pharmacopeias information such as European Pharmacopeia, Japan Pharmacopeia and US Pharmacopeia. Database includes drug based bioanalytical methods covering most required fields and external database links of important drug portals such as drug bank, Rxlist, MEDLINE plus, KEGG Drug ID, KEGG Compound ID, Merck manual, PubChem compound ID, PubChem substance ID and USFDA. Searching/querying the database is through drug name, chemical formula or structural search by smiles format. Keen selections of bioanalytical methods for pharmaceutical analysis or regular quality control are also possible with E-BABE. E-BABE was built understanding the needs of pharmaceutical industry and laboratories including CROs working on BA/BE studies. Presently it has nearly of 5,000 methods and it will be updated regularly.
- NeuroImmunology and Neuroinflammation
Session Introduction
Ramachandran Muthiah
Consultant Physician & Cardiologist
Title: Neurochemistry of COVID-19 Infectuin
Biography:
Ramachandran Muthiah, Consultant Physician & Cardiologist, Zion hospital, Azhagiamandapam and Morning star hospital, Marthandam, Kanyakumari District, India. Mother Swornam belongs to keezhkulam village and Father Muthiah belongs to Enayam thoppu and both were farmers. Published many papers in Cardiosource, American College of Cardiology Foundation, Case Reports in Clinical Medicine (SCIRP) and Journal of saudi heart association.
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus disease 2019 (COVID-19), the presentation of patients with extremely low blood oxygenation, but no sensation of dyspnea and can suffer sudden death after voluntary “breaks” from the oxygen supplementation. Recognizing “happy hypoxia” as a feature of COVID-19 pneumonia has been associated with neurological syndromes such as meningoencephalitis, ischemic stroke, encephalopathy, Guillain-Barré syndrome (GBS), acute necrotizing encephalopathy, and acute disseminated encephalomyelitis (ADEM) and possible mechanisms implicated in these neurological conditions are neuronal injury associated with direct virus infection, hyperinflammation syndrome associated with cytokine storm, a para- or post-infectious inflammatory disease, an immune-mediated disease, or a secondary process due to severe effects of a systemic disorder.